Carnet bibliographique 53

P 53 ( Protein 53 kDa )

Protein Description 393 amino acids; 53 kDa phosphoprotein; contains, from N-term to C-term, a transactivation domain, a DNA-binding domain, nuclear localization signals and a tetramerization domain. Expression Widely expressed. Localisation Nucleus. Function Tumour suppressor gene; P53 is a transcriptional regulator acting as a guardian of the genome; in response to DNA damage, p53 is overexpr...

P 53 ( Protein 53 kDa )

پیوستها 53

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The accelerating trend toward Faster, Better, Cheaper (FEE) missions places increasing emphas is on the trade-offs between requirements and risk to reduce cost and development times, while still improving quality and reliability. The Risk/Requirenlents Trade-off Guidelines discussed in this paper are part of an integrated approach to address the main issues by focusing on the sum of prevention,...

جلد 53